SURUNKALI TROMBOEMBOLIK O‘PKA GIPERTENZIYASI: PATOGENEZDAN DAVOLASH STRATEGIYASINI TANLASHGACHA
DOI:
https://doi.org/10.5281/zenodo.23195254Keywords:
surunkali tromboembolik o‘pka gipertenziyasi, patogenez, maxsus terapiya, o‘pka endarterektomiyasi, ballonli o‘pka angioplastikasi, multimodal yondashuvAbstract
Ushbu maqolada terapevtik yondashuvlar uchun asos bo‘ladigan surunkali tromboembolik o‘pka gipertenziyasi (KTG) patogenezi bo‘yicha ma’lumotlar keltirilgan. KTG odatda katta va yoki o‘rta o‘lchamdagi o‘pka arteriyalarining uyushgan tromblar tomonidan doimiy ravishda tiqilib qolishi bilan boshlanadi. Tromblarning yo‘qolishining buzilishi g‘ayritabiiy fibrinoliz yoki gematologik yoki autoimmun kasalliklar bilan bog‘liq bo‘lishi mumkin. Kichik tomirlarning shikastlanishining asosiy molekulyar mexanizmlari hali to‘liq tushunilmagan. Kichik tomirlar kasalligining darajasi KTGning og‘irligiga va operatsiyadan keyingi natijalarga sezilarli ta’sir qiladi. STO‘Gni davolash usullari uchta yondashuv — o‘pka arteriyasi endarterektomiyasi, o‘pka arteriyalari ballonli angioplastikasi va o‘pka arterial gipertenziyasini davolashda qo‘llaniladigan maxsus terapiyalar — rivojlanishi natijasida takomillashib bordi. Maqolada ushbu toifadagi bemorlarni davolashda ko‘p usulli yondashuvning imkoniyatlari yoritib berilgan.References
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