YURAK-QON TOMIR KASALLIKLARIDA ANTIKOAGULYANT PREPARATLARNING SAMARADORLIGI VA GEMORRAGIK ASORATLAR XAVFI
DOI:
https://doi.org/10.5281/zenodo.23553478Keywords:
anticoagulants, warfarin, apixaban, rivaroxaban, atrial fibrillation, bleeding, HAS-BLED, thromboembolismAbstract
This narrative review evaluates the efficacy of anticoagulant therapy and the risk of hemorrhagic complications in cardiovascular diseases based on Uzbekistan’s national clinical protocols and international evidence. Stroke prevention in atrial fibrillation, anticoagulant selection in patients with mechanical heart valves, and the benefits and limitations of direct oral anticoagulants (DOACs) compared with vitamin K antagonists are examined. The importance of the HAS-BLED score, renal function, concomitant medications, and treatment adherence in bleeding risk assessment is highlighted. The study is based on a descriptive review of the literature and clinical recommendations; no original clinical observations or patient data were collected.References
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