PEDIATRIK VA GERIATRIYA AMALIYOTIDA INDIVIDUAL DORI SHAKLLARINI YARATISH VA ZAMONAVIY FARMATSEVTIK TEXNOLOGIYALAR
DOI:
https://doi.org/10.5281/zenodo.23643019Keywords:
pediatriya, geriatriya, individual dori shakli, ekstemporal tayyorlash, 3D bosib chiqarish, yordamchi modda, dozani moslashtirishAbstract
Ushbu maqolaning maqsadi pediatrik va geriatriya amaliyotida individual dori shakllarini yaratishning ilmiy asoslarini hamda zamonaviy farmatsevtik texnologiyalar yordamida bemorga moslashtirilgan terapiyani kuchaytirish imkoniyatlarini tahlil qilishdan iborat. Metodologiya sifatida klinik-farmatsevtik ehtiyojlarni xaritalash, yordamchi moddalarning xavfsizlik profili bo‘yicha qiyosiy baholash, dozalash aniqligi va barqarorlikka oid nazariy modellashtirish, shuningdek, ekstemporal va yarim sanoat jarayonlari uchun sifatni boshqarish ko‘rsatkichlarini sintez qilish qo‘llanildi. Natijalar individual dori shakllarida dozani moslashtirish, yutish qulayligi, ta’mni maskirovka qilish, dori-dori o‘zaro ta’siri va polifarmatsiya xavflarini kamaytirishning texnologik yo‘llarini tizimlashtiradi. Ilmiy yangilik sifatida pediatriya va geriatriyada «bir bemor — bir texnologik profil» yondashuvi, 3D bosma va mikrodozalash konsepsiyasini ekstemporal amaliyotga integratsiya qilish mezonlari hamda xavfga asoslangan sifat atributlari taklif etiladi.References
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